Born January 2, 1801, to Peter and Susan Wagneseller in Montgomery county; a physician by profession. He was liberally educated having graduated at the University of Pennsylvania. He established himself in the practice of medicine in his native county, but about 1827 located at Selinsgrove, Snyder (then Union) County. In addition to practicing medicine, he carried on the mercantile business, keeping a general store and dealing extensively in grain. For quite a number of years he was in partnership with his brother, William F. Wagenseller, in the old stand at the canal when nearly all the product of Snyder county was hauled to Selinsgrove. He was thus engaged at the time of his death which occurred at Selinsgrove April 27, 1847. He had abandoned his profession some years previously. He was a man of fine business qualities and made a success in life. He became prominent in public affairs. Member of House of Representatives, Union County. He was a whig and as such was elected to the State Senate in which body his intelligence made him a useful member. He was active in party affairs, and a man of influence in the community, as well as a leading spirit in every movement calculated to develop the resources of the county and advance the interests of Selinsgrove. He served two terms in the Senate, being a member at the time of his death, representing Juniata, Mifflin and Union Counties. On January 27, 1829, he was married by Rev. Daniel Weiser to Mary Richter, born Dec. 25, 1810, a daughter of Peter Richter, a man who was prominent and influential about Selinsgrove. Mary died March 4, 1863. Their union was blessed with eight children.