PRINTER'S NO. 2362

THE GENERAL ASSEMBLY OF PENNSYLVANIA

HOUSE RESOLUTION

No.

467

Session of

2017

INTRODUCED BY M. QUINN, CORR, BAKER, BIZZARRO, BOBACK, BRADFORD,

V. BROWN, CALTAGIRONE, D. COSTA, DAVIS, DiGIROLAMO, DRISCOLL,

DUSH, GILLEN, HENNESSEY, PHILLIPS-HILL, KINSEY, LONGIETTI,

Designating the month of July 2017 as "Fragile X Syndrome

Awareness Month" in Pennsylvania.

WHEREAS, Fragile X syndrome is an inherited genetic condition

that causes intellectual and developmental disabilities; and

WHEREAS, Affecting approximately 1 in 4,000 males and 1 in

8,000 females, fragile X syndrome causes varying degrees of

intellectual disability and a range of behavioral issues and

medical conditions; and

WHEREAS, Mild to severe mutation in the fragile X mental

retardation 1 (FMR1) gene on the X chromosome is the single

intellectual disability in females; and

WHEREAS, Related disabilities range from moderate learning

disabilities to more severe intellectual disabilities; and

WHEREAS, Affected individuals often experience delayed speech

and language development; and

WHEREAS, Repetitive behaviors, poor impulse control,

depression, shyness and avoidance of social situations are some

of the potential behavioral manifestations; and

WHEREAS, Mitral valve prolapse and seizures are among the

related physical conditions; and

to a full mutation in subsequent generations; and

WHEREAS, Specialists in pediatrics, molecular genetics,

psychiatry, psychology, neurology, genetic counseling, speech

and language pathology, occupational therapy, neurobiology,

pathology and social work contribute to our understanding of

fragile X syndrome; and

WHEREAS, Research focuses on the fragile gene as expressed in

persons with the syndrome and as carried by persons with the

premutation; and

WHEREAS, Related clinical trials and safety studies are being